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. 1998 Aug 1;112(2):199–210. doi: 10.1085/jgp.112.2.199

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Properties of the four gating modes of the m₂ receptor-activated K_ACh channel. Three different parameters: mean open time (A), frequency of channel openings (B), and mean open probability (C) were evaluated with regard to modal behavior of the channel after muscarinic receptor stimulation. The values for the mean open time of each gating mode are: t _1open = 2.28 ± 0.10, t _2open = 2.75 ± 0.08, t _3open = 3.53 ± 0.19, and t _4open = 6.24 ± 0.38 ms. The values for the frequency of channel openings are: f ₁ = 2.5, f ₂ = 10.3 ± 0.1, f ₃ = 31.7 ± 0.3, and f ₄ = 69.1 ± 1.2 Hz. The values for the mean open probability are: P _o1= 0.0057 ± 0.0003, P _o2 = 0.0281 ± 0.0010, P _o3 = 0.1128 ± 0.0065, and P _o4 = 0.4341 ± 0.0195. Data are mean ± SEM (n = 231–1,116).