Figure 5.
Average cluster properties. Solid lines are Gaussians fitted only to the indicated range of bins. (left) The average desensitization rate constant (τc P o)−1 of the main population is 4.6 s−1. (right) The average cluster frequency of the main population is 0.078 s−1. This value divided by the number of channels in the patch (∼10) is an estimate of the rate constant for recovery from desensitization for diliganded AChR (53 patches; 2–1,000 μM ACh).