. 2008 Aug;89(4):251–263. doi: 10.1111/j.1365-2613.2008.00597.x

Table 2.

Macroscopic and laboratory features of all experimental groups: common bile duct ligation

	Sham-operated 6 weeks (n = 4)	CBDL 1 week (n = 6)	CBDL 3 weeks (n = 6)	CBDL 4 weeks (n = 6)	CBDL 5 weeks (n = 6)	CBDL 6 weeks (n = 6)
Liver weight (g/10 g BW)	0.40 ± 0.05	0.77 ± 0.07^*	0.68 ± 0.12^*	0.78 ± 0.06^*	0.76 ± 0.06^*	0.70 ± 0.81^*
Spleen weight (g/10 g BW)	0.035 ± 0.003	0.054 ± 0.004^*	0.085 ± 0.013^*	0.109 ± 0.007^*	0.094 ± 0.006^*	0.085 ± 0.011^*
AST (IU/l)	35 ± 7	285 ± 58^*	730 ± 179^*^†	655 ± 135^*^†	518 ± 122^*^†	647 ± 151^*^†
ALT (IU/l)	4. ± 0.2	206 ± 14^*	332 ± 90^*	370 ± 57^*	430 ± 68^*	241 ± 68^*
Bilirubin (mg/dl)	0.3 ± 0.1	12 ± 2^*	12 ± 2^*	9 ± 3^*	16 ± 4^*	13 ± 1^*

Values given are mean ± SEM. CBDL, common bile duct ligation; BW, body weight; AST, aspartate aminotransferase; ALT, alanine aminotransferase.

P < 0.05 vs. sham-operated.

^†

P < 0.05 vs. CBDL 1 week.