Figure 12.
ES/NOMAD evolution of pacemaker neuron model. (A) Evolution of best error value found by Random (red) and hybrid ES+NOMAD (blue) searches. The data points (mean ± sdv) are averaged over 10 different runs of the algorithms using different random seeds. After 500 error evaluations Neurofitter switched from ES to NOMAD. (B) The evolution of the best maximal NaP and Kdr channel conductances during the same 10 runs as in A for the hybrid ES + NOMAD algorithm. The dashed line shows the maximal conductance of the target data. Not the entire range of the y-axis is shown to allow a better scaling of the plot.