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Formate accumulation profiles in the different types of glucose limited fed-batch cultivations of E. coli W3110 without supplementation of the trace elements selenium, nickel and molybdenum. The data are from the standard glucose-limited fed-batch reference cultivation (○), from the cultivation with the STR-PFR (△), and from the cultivation with a permanent oxygen down-shift (□). Zero hours indicates the time of the feed start.
