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. Author manuscript; available in PMC: 2008 Aug 28.
Published in final edited form as: Biochemistry. 2006 Dec 12;45(49):14726–14739. doi: 10.1021/bi061535t

Figure 1. Topology of Cdr1p and sequence alignment of Walker B and extended Walker B motifs from various ABC transporters.

Figure 1

The sequence alignment of Walker B and extended Walker B motifs residues in NBDs with those from other nucleotide binding domains of some known ABC transporters. The conserved Asp and Asn residue within and adjacent the Walker B motifs, respectively, of fungal NBDs and the equivalent Asp/Glu in non-fungal NBDs is shown in bold and underlined.