Table 1.

Inclusion Criteria for Study Groups

FE

At least 1 SOPS positive symptom score of 6 for at least 1 week, irrespective of basic symptoms

UHR

Any SOPS positive symptom score between 3 and 5, at least once per week over the past month, with beginning in past year or scoring 1 scale point higher compared with 12 months ago (=Attenuated Positive Prodromal Syndrome)

Any SOPS positive symptom score of 6 for less than 1 week (=Brief Intermittent Psychotic Syndrome)

First-degree relative with any psychotic disorder and/or patient meeting DSM-IV Schizotypal Personality Disorder criteria and a 30% or greater drop in the GAF score during the last month compared with 12 months ago (=Genetic Risk and Deterioration Syndrome)

All UHR criteria irrespective of basic symptoms

BS

Presenting at least 1 predictive basic symptom4 with an SPI-A score of at least 3, not meeting any UHR or FE criteria (predictive basic symptoms: thought interference; thought perseveration; thought pressure; thought blockages; disturbances of receptive language; decreased ability to discriminate between ideas and perception, fantasy, and true memory; unstable ideas of reference; derealization; visual and acoustic perception disturbances)

PCo

Patients meeting none of the criteria for BS, UHR, or FE groups

Note: FE, first-episode group; SOPS, Scale of Prodromal Symptoms (SOPS positive symptoms: unusual thought content/delusional ideas, suspiciousness/persecutory ideas, grandiose ideas, perceptual abnormalities/hallucinations, disorganized communication); UHR, ultra high-risk group; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; GAF, Global Assessment of Functioning²⁹; BS, basic symptom at-risk group; SPI-A, Schizophrenia Prediction Instrument—Adult Version; PCo, patient control group.