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. 2008 Sep 1;205(9):2111–2124. doi: 10.1084/jem.20072076

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© 2008 Das et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 5. — CD28 is down-regulated in CD8 T cells from patients with high viral load. (a) Representative dot plot to show the coexpression of CD28 and CD3ζ in CD8 T cells in a patient with high viral load. (b) Flow cytometric histogram to show the proportion of CD8 T cells that are CD28⁺ in a patient with high viral load (gray) and a healthy donor (dashed line). (c) Cumulative data for CD28 expression is shown against viral load, HBeAg status, and ALT level.

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