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. 2008 Sep 1;205(9):2163–2175. doi: 10.1084/jem.20080578

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© 2008 Qian et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 9. — Ablation of Apc results in the accumulation of β-catenin in hematopoietic cells in vivo. (A) Expression of β-catenin in Thymus (T) and Spleen (SP) from CM 4 d after induction (two doses). (B) Expression of intracellular β-catenin in subsets of BM cells from Mx1-Cre⁻Apc^fl/fl (blue profile) and Mx1-Cre⁺Apc^fl/fl (red profile) CM 4 d after induction (two doses). Data are representative of three independent experiments.