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. 2008 Sep;125(1):101–110. doi: 10.1111/j.1365-2567.2008.02825.x

Figure 2.

Figure 2

ISO-1 has no significant effect on cytokine release from MDMs. Human monocyte-derived macrophages were pretreated with ISO-1 (50 μm) or DMSO for the times shown, prior to addition of LPS (1 ng/ml) for a further 24 hr, with ISO-1 remaining present throughout the time course. Cell free supernatants were collected and (a) TNF-α or (b) CXCL8 content assayed by ELISA. No significant inhibition of cytokine release by ISO-1 was found. Data are mean ± SEM from three separate experiments from different donors and analysed by two-way anova with Bonferroni's post-test.