Figure 11.

Schematic diagram of molecular links between the functions of SNL1, GLE2, NUP116, NUP100, NIC96, and POM152. The dashed lines indicate a synthetic lethal phenotype between mutant alleles, the dashed lines with arrowheads indicate high-copy suppression of a mutant allele by a wild-type gene (with the orientation pointing toward the conditional phenotype of the gene being suppressed), and the solid line indicates direct in vitro protein–protein interactions.