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. Author manuscript; available in PMC: 2008 Aug 28.
Published in final edited form as: J Med Chem. 2006 Oct 19;49(21):6283–6289. doi: 10.1021/jm060564z

Table 2.

Hollow Fiber Activities of Indenoisoquinoline Analogues.

compound IP scorea SC scorea total score cell killb
1 2 6 8 Y
2 16 4 20 N
10 16 2 18 N
11 4 2 6 N
13 6 0 6 N
16 12 2 14 N
17 8 0 8 N
a

The IP and SC scores listed are the sums of all the IP and SC scores for each compound.

b

A net cell kill at one or more implant sites is indicated with a Y.