Figure 3.

The surface of carboxylate QDs was successfully functionalized with the cleavable PA construct. Mobility of QDs modified with the cleavable PA construct (lane 4, diffuse band) is reduced compared with that of unmodified QDs (lane 3). 24 h exposure of the QD-PA conjugates to MMP-7 (lane 5) leads to a partial recovery of mobility, Increased mobility after exposure to MMP-7 can be completely inhibited by the addition of 30 mM EDTA (lane 6). This image is representative of three independent trials.