Table 1.
Partial | 1ary GTC | G myoclonic | G absence | ||
---|---|---|---|---|---|
A | Phenytoin | + | + | - | - |
Carbamazepine | + | + | - | - | |
Valproate | + | + | + | + | |
Phenobarbital | + | + | - | - | |
Primidone | + | + | + | - | |
Ethosuximide | - | - | - | + | |
Methsuximide | + | ? | ? | + | |
Clonazepam | + | + | + | + | |
B | Felbamate | +b | + | ? | ? |
Gabapentina | +b | - | - | - | |
Lamotriginea | +b | +b | ? | +b | |
Topiramatea | +b | +b | ? | ? | |
Tiagabine | +b | ? | - | - | |
Oxcarbazepinea | +b | +? | - | - | |
Levetiracetama | +* | +b | +b | ? | |
Zonisamide | +b | + | + | ? | |
Pregabalin | +b | ? | - | - |
New AED with positive initial monotherapy trials.
New AED efficacy indication supported by blinded trials.