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Inhibition of the synthesis of DNA in uterine leiomyoma cells by Ad.p27. The antiproliferative effects were determined after transfecting uterine leiomyoma cells for 24 hr with Ad.null and Ad.p27 adenoviral vectors and labeling with BrdU (10 µM) for 24 hr. Results are expressed as percentage inhibition of BrdU incorporation relative to control cells. Values are the means (±SD) of three experiments with triplicate determinations. *, p<0.05; **, p<0.01.
