Figure 2.

FN or LAM significantly increased cathodal directedness of migration. The enhancement was concentration dependent. **, p < 0.01; *, p < 0.05 compared with that on the noncoated substratum in same EFs (shown at right). Directedness of 0 indicates random migration; directedness of 1 indicates all cells migrated directly cathodally; and −1 indicates direct anodal migration of all cells along the field vector. For methods of determining directedness, see Zhao et al. (1996a). Number of cells for each point, 43∼221.