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Tissue atrophy in aged rTg3696AB mice. Histological images indicate substantial loss of neurons in rTg3696AB mice between 11 and 13 months. Representative photomicrographs depict hippocampus (top) and cortex (bottom) after processing with H&E. Boxes indicate area shown at higher magnification. Original magnifications: ×5 (A, B, top); ×40 (A, B, bottom).
