FIGURE 1.

Schematic map of Htt and AR constructs, with location of pentapeptide motifs. A construct containing the first 136 amino acids of the Htt protein was fused to YFP. A pentapeptide motif (¹²³FQKLL¹²⁷) is present C-terminal to the polyglutamine tract. A construct containing the first 127 amino acids of AR was fused to YFP. A pentapeptide motif (²³FQNLF²⁷) is present N-terminal to the polyglutamine tract. Amino acids immediately flanking the motifs are shown and have no homology. A full-length AR-YFP construct (not drawn to scale) is also pictured.