Experiment 1: Expression of α1d ADR mRNA in the CA1, CA2 and CA3 hippocampal subfields, and lateral (DGlb) and medial (DGmb) blades of the dentate gyrus, 1, 3, 7 or 14 days after bilateral adrenalectomy (ADX; n = 4/group) or sham operation (Sham; n = 3/group; Experiment 1). Additional animals remained untreated (naïve; n = 4) or were given the saline-dextrose solution to drink, but did not undergo surgery (UNOP; n = 3). * p < 0.001 for ADX versus Naïve, UNOP and Sham groups; † p < 0.05 for UNOP and Sham groups versus Naïve. Two way ANOVA indicated that there were no significant effects of time or a time by surgery interaction.