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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Aging Cell. 2008 Mar 24;7(3):355–367. doi: 10.1111/j.1474-9726.2008.00393.x

Figure 4.

Figure 4

Cell senescence and apoptosis contribute to the cellular aging phenotype of cells expressing elevated levels of wild-type lamin A. A. The percentage of senescent cells at passage 5 through 12 was determined by staining for senescence-associated β-galactosidase as described in Materials and Methods. B. The percentage of apoptotic cells at passage 7 through 12 was determined by Tunnel assays as described in the supplementary Materials and Methods. Data shown represent mean +/− standard deviation of three independent measurements.