TABLE 2.

Single molecule burst rates in varying DNA mixtures

	1 pM 4 kbp	1 pM 8 kbp	0.5 pM 4 kbp +0.5 pM 8 kbp	0.25 pM 4 kbp + 0.75 pM 8 kbp
Traditional SMD	305	420	381	410
CICS	915	928	948	922

Simulated burst rate of DNA mixtures taken using traditional SMD and CICS. The burst rate of traditional SMD varies as relative proportions of the two DNA components are varied although the total concentration is conserved in all cases. The CICS burst rate remains consistent across the mixtures. The applied threshold was 30 counts. Bin time, 0.1 ms.