Table 3.
Lung function abnormalities in patients with common variable immunodeficiency. The results are given as normal/mild/moderate/severe in the degree of obstructive disease and degree of restrictive disease lines (see Patients and methods; 90 patients evaluated) and no/partial/global in the respiratory insufficiency degree line (88 patients evaluated).
| Normal | Low | Deficient | N versus L versus D P-value | N versus L+D P-value | N+L versus D P-value | |
|---|---|---|---|---|---|---|
| Obstructive disease | 29 | 5 | 8 | 0·132* | 0·277** | 0·789** |
| Degree of obstructive disease | 27/18/8/3 | 13/2/2/1 | 8/3/5/0 | 0·274* | 0·408* | 0·620* |
| Restrictive disease | 8 | 3 | 2 | 0·859* | 0·999** | 0·999** |
| Degree of restrictive disease | 48/7/1/0 | 15/2/1/0 | 14/2/0/0 | 0·869* | 0·904* | 0·783* |
| Respiratory insufficiency | 3 | 4 | 3 | 0·029* | 0·041** | 0·380** |
| Degree of respiratory insufficiency | 51/2/1 | 14/4/0 | 13/2/1 | 0·034* | 0·033* | 0·291* |
*
Spearman's test;
**
Fisher's exact test. N, normal; L, low; D, deficient serum mannan-binding lectin levels.