Table 3.
Criteria for evaluating spinal cord regeneration experiments (National Institute of Neurological and Communicative Disorders and Stroke Guidelines)
| Key criteria to assess axonal regeneration after experimental SCI | |
|---|---|
| 1. | The experimental lesion must cause disconnection of nerve processes |
| 2. | Processes of CNS neurons must bridge the level of injury |
| 3. | The regenerated fibres must make Synaptic contacts |
| 4. | The regenerated fibres must generate post-synaptic responses |
| 5. | Functional responses must derive from regenerated connections |