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. Author manuscript; available in PMC: 2008 Sep 1.
Published in final edited form as: Brain Dev. 2007 May 24;29(10):609–616. doi: 10.1016/j.braindev.2007.04.001

Table 4.

Prevalence of any sleep problem by mutation type for each questionnaire year.

Mutation Classification Sleeping
Problems
Prevalence
n (%) 2000		 Sleeping
Problems
Prevalence
n (%) 2002		 Sleeping
Problems
Prevalence
n (%) 2004
No Mutation 31 (91.2) 31 (68.9) 32 (76.2)
p.T158M 13 (92.9) 14 (93.3) 11 (78.6)
p.R168X 14 (93.3) 14 (87.5) 16 (88.9)
p.R294X 9 (100.0) 12 (100.0) 13 (86.7)
p.R270X 11 (91.7) 11 (78.6) 11 (84.6)
p.R255X 8 (100.0) 5 (71.4) 9 (90.0)
p.R133C 4 (66.7) 8 (88.9) 9 (90.0)
p.R306C 7 (100.0) 8 (88.9) 9 (100.0)
p.R106W 3 (100.0) 1 (50.0) 3 (75.0)
Other 9 (81.8) 12 (92.3) 10 (76.9)
Early Truncating 7 (87.5) 9 (81.8) 8 (80.0)
Large Deletion 5 (100.0) 8 (100.0) 8 (100.0)
C Term 11 (78.6) 12 (80.0) 13 (76.5)
Total with Sleeping Problem 132 (90.4) 145 (82.4) 152 (83.1)

Note: Denominator is cases tested for mutations for each year: Year 2000 = 146; Year 2002 = 176; Year 2004 = 183