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. 2008 Sep 12;3(9):e3204. doi: 10.1371/journal.pone.0003204

Figure 1. P. g and/or high fat diet increases aortic atherosclerotic lesions in ApoE+/−-TLR2+/+ mice when compared to ApoE+/−-TLR2+/−, and ApoE+/−-TLR2−/− mice.

Figure 1

En face analysis: (1A–1I): Representative en face view of aortic surface lesions in ApoE+/−-TLR2+/+, ApoE+/−-TLR2+/−, and ApoE+/−-TLR2−/− mice after 24 weeks of treatments. (1J): Calculated percentages of aortic surface area covered by lesions after 24 weeks of treatments (bacterial challenge or vehicle control) among mice of three genotypes maintained on standard chow or high fat diets. Values represent means±SD; *p<0.05 for ApoE+/−-TLR2+/+ mice compared to ApoE+/−-TLR2+/− mice and **p<0.05 for ApoE+/−-TLR2+/+ mice compared to ApoE+/−-TLR2−/− mice in the same treatment condition and maintained on the same diet. Abbreviations are as defined in the text.