Table I.
Initial and final body weights and blood glucose concentrations in control mice and diabetic mice with and without the peroxynitrite decomposition catalyst FeTMPS treatment.
Body weight (g)
|
Blood glucose (mmol/l)
|
|||
---|---|---|---|---|
Initial | Final | Initial | Final | |
Control | 20.6±0.40 | 29.0±0.95 | 7.90±0.17 | 8.00±0.20 |
Control + FeTMPS (5 mg/kg/day) | 20.3±0.50 | 27.0±0.70 | 7.70±0.33 | 7.90±0.12 |
Control + FeTMPS (10 mg/kg/day) | 20.7±0.47 | 28.0±0.90 | 8.35±0.27 | 8.05±0.24 |
Diabetic | 20.2±0.33 | 24.9±0.53a | 14.40±0.70a | 33.00±0.20a |
Diabetic + FeTMPS (5 mg/kg/day) | 20.9±0.33 | 25.0±0.40a | 15.30±0.70a | 32.40±0.50a |
Diabetic + FeTMPS (10 mg/kg/day) | 20.6±0.60 | 24.6±0.80a | 14.20±0.90a | 32.60±0.40a |
Data are the means ± SEM, n=8–14 per group.
Significantly different from the controls (p<0.01)