Table I.
Mouse | Latencya (days) | Spleen weight (g) | Liver weight (g) |
Ba/F3 injected | |||
A1 | >90b | 0.04 | 1.18 |
A2 | >90b | 0.05 | 1.35 |
A3 | >90b | 0.05 | 1.51 |
A4 | >90b | 0.05 | 1.36 |
A5 | >90b | 0.06 | 1.45 |
A6 | >90b | 0.05 | 1.73 |
p185wt injected | |||
A1 | 18 | —c | —c |
A2 | 20 | 0.16 | 3.00 |
A3 | 20 | 0.18 | 2.98 |
A4 | 20 | 0.16 | 3.39 |
B1 | 13 | —c | —c |
B2 | 14 | —c | —c |
B3 | 16 | 0.21 | 3.24 |
B4 | 16 | 0.19 | 2.88 |
B5 | 16 | 0.18 | 3.29 |
B6 | 19 | —c | —c |
Abi1 shRNA injected | |||
A1 | 32 | —c | —c |
A2 | 34 | 0.03 | 1.89 |
A3 | 37 | 0.04 | 1.23 |
A4 | 37 | 0.06 | 1.15 |
A5 | 37 | 0.05 | 1.70 |
A6 | 37 | 0.06 | 1.76 |
A7 | 37 | 0.07 | 1.63 |
Latency is defined as the time after injection that mice died or become moribund.
The mice injected with Ba/F3 cells survived >90 days without any disease observed.
The mice dead prior to the pathology analysis.