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. 2008 May 2;29(9):1717–1724. doi: 10.1093/carcin/bgn098

Table I.

Summary of the disease development in mice injected with p185wt/BaF3 cells and the p185wt/BaF3 cells expressing Abi1 shRNA

Mouse Latencya (days) Spleen weight (g) Liver weight (g)
Ba/F3 injected
    A1 >90b 0.04 1.18
    A2 >90b 0.05 1.35
    A3 >90b 0.05 1.51
    A4 >90b 0.05 1.36
    A5 >90b 0.06 1.45
    A6 >90b 0.05 1.73
p185wt injected
    A1 18 c c
    A2 20 0.16 3.00
    A3 20 0.18 2.98
    A4 20 0.16 3.39
    B1 13 c c
    B2 14 c c
    B3 16 0.21 3.24
    B4 16 0.19 2.88
    B5 16 0.18 3.29
    B6 19 c c
Abi1 shRNA injected
    A1 32 c c
    A2 34 0.03 1.89
    A3 37 0.04 1.23
    A4 37 0.06 1.15
    A5 37 0.05 1.70
    A6 37 0.06 1.76
    A7 37 0.07 1.63
a

Latency is defined as the time after injection that mice died or become moribund.

b

The mice injected with Ba/F3 cells survived >90 days without any disease observed.

c

The mice dead prior to the pathology analysis.