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Determination of ΔCp for the binding of four peptides to PDZ3. Temperature-dependent values for ΔH were fit with linear curves, where the value for the slope is ΔCp. (A) CRIPT-derived peptides: YKQTSV (λ), curve: y = −163x – 2497; DTKNYKQTSV (σ) y = −160x – 3154; (B) Neuroligin-derived peptides: HSTTRV (λ), y = −131x – 3235; HPHSHSTTRV (σ), y = −128x – 5221. Error ranges, when graphed, are about the dimension of the data point symbols; for visual clarity, error bars are not shown.
