. Author manuscript; available in PMC: 2008 Sep 2.

Published in final edited form as: Biochemistry. 2007 May 3;46(21):6340–6352. doi: 10.1021/bi062088k

Table 3.

Thermodynamic binding parameters for PDZ3 and N-acetylated CRIPT- and neuroligin-based peptides determined by ITC.^a

	peptide	K_d (μM)	ΔG (kcal/mol)	ΔH (kcal/mol)	TΔS (kcal/mol)
1	Ac-YKQTSV	3.3 ± 0.1	−7.5 ± 0.1	−7.4 ± 0.2	0.1 ± 0.2
2	Ac-NYKQTSV	9.9 ± 1.4	−6.8 ± 0.1	−7.3 ± 0.1	−0.5 ± 0.1
3	Ac-HSTTRV	55 ± 7	−5.8 ± 0.1	−4.5 ± 0.3	1.3 ± 0.4
4	Ac-SHSTTRV	70 ± 1	−5.7 ± 0.5	−4.5 ± 0.5	1.2 ± 0.1

Values are the arithmetic mean of at least two independent experiments. All c values measured between 5 and 65. Stoichiometric (n) values ranged from 0.91 to 1.12.