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. 2008 Jul 29;99(3):481–487. doi: 10.1038/sj.bjc.6604523

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Copyright © 2008 Cancer Research UK

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Relative thymidine kinase (TK)-1 activity in MDA MB231 breast cancer cells after addition of (A) dCTP and (B) KIN52. Cells were exposed to IC₅₀ concentrations of 5-fluorouracil (), doxorubicin () and paclitaxel (▪), and compared with untreated cells (□). % cells are normalised to TK activity before addition of dCTP or KIN52 (set to 100%).

Inline graphic — Relative thymidine kinase (TK)-1 activity in MDA MB231 breast cancer cells after addition of (A) dCTP and (B) KIN52. Cells were exposed to IC₅₀ concentrations of 5-fluorouracil (), doxorubicin () and paclitaxel (▪), and compared with untreated cells (□). % cells are normalised to TK activity before addition of dCTP or KIN52 (set to 100%).