Table 2. Patient characteristics at baseline (patients treated at the MTD).
| Characteristic | Value |
|---|---|
| No. of patients | 29 |
| Median age (range) (years) | 57 (40–73) |
| Sex, n (%) | |
| Male | 25 (86) |
| Female | 4 (14) |
| Primary tumour site, n (%) | |
| Colon | 15 (52) |
| Rectum | 9 (31) |
| Rectosigmoid | 5 (17) |
| WHO performance status, n (%) | |
| 0 | 15 (52) |
| 1 | 11 (38) |
| 2 | 1 (3) |
| Unknown | 2 (7) |
| Prior surgical resection, n (%) | |
| Radical | 9 (31) |
| Palliative | 10 (34) |
| Defunctioned only | 2 (7) |
| None | 8 (28) |
| No. of measurable lesions (%) | |
| 1 | 1 (3) |
| 2 | 7 (24) |
| ⩾3 | 21 (72) |
MTD=maximum tolerated dose; WHO=World Health Organization.