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. 2008 Jul 29;99(4):611–615. doi: 10.1038/sj.bjc.6604524

Table 2. Occurrence of invasive cancers at specific sites subsequent to breast carcinoma in situ.

Site Observed Expected SIR 95% CI
Head and neck 19 25.03 0.76 0.46–1.19
Oesophagus 22 22.85 0.97 0.60–1.46
Stomach 26 32.82 0.79 0.52–1.16
Colorectal 130 147.93 0.88 0.73–1.04
Pancreas 22 37.20 0.59 0.37–0.90
Lung 101 133.92 0.75 0.61–0.92
Malignant melanoma 14 21.80 0.64 0.35–1.08
Breast 512 261.44 1.96 1.79–2.14
Cervix uteri 12 20.39 0.59 0.30–1.03
Corpus uteri 74 52.14 1.42 1.11–1.78
Ovary 49 59.81 0.82 0.61–1.08
Kidney 16 16.02 1.00 0.57–1.62
Bladder 22 30.13 0.73 0.46–1.11
Non-Hodgkin's lymphoma 24 35.56 0.67 0.43–1.00
Multiple myeloma 11 16.00 0.69 0.34–1.23
Leukaemia 20 24.93 0.80 0.49–1.24
Othersa 72 138.28 0.52 0.41–0.66
All sitesa 1146 1076.25 1.06 1.00–1.13

CI=confidence interval; SIR=standardised incidence ratio.

a

Excluding non-melanoma skin cancers.