TABLE 1.
Class II Locus | Sequence position | Molecular location | Surface exposure | 3.0 Angstrom patches | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
DRB | 4 | Side | ++ | 3 | 4 | 5 | |||||
DRB | 6 | Side | + | 5 | 6 | 7 | A15 | A17 | |||
DRB | 12 | Underside | ± | 11 | 12 | 13 | 29 | ||||
DRB | 14 | Underside | + | 13 | 14 | 15 | 16 | 27 | 29 | ||
DRB | 16 | Underside | + | 15 | 16 | 17 | 18 | 25 | |||
DRB | 18 | Side | + | 17 | 18 | 19 | 23 | ||||
DRB | 25 | Side | ++ | 16 | 24 | 25 | 26 | 43 | |||
DRB | 26 | Side | ± | 25 | 26 | 27 | 42 | ||||
DRB | 31 | Underside | + | 10 | 29 | 30 | 31 | 32 | |||
DRB | 32 | Underside | + | 31 | 32 | 33 | 35 | ||||
DRB | 33 | Underside | + | 8 | 32 | 33 | 34 | ||||
DRB | 34 | Side | ++ | 33 | 34 | 35 | A83 | ||||
DRB | 40 | Side | + | 28 | 39 | 40 | 41 | ||||
DRB | 41 | Side | + | 40 | 41 | 42 | 43 | 44 | 45 | ||
DRB | 44 | Side | + | 41 | 43 | 44 | 45 | ||||
DRB | 47 | Side | + | 28 | 46 | 47 | 48 | 62 | |||
DRB | 48 | Side | ++ | 47 | 48 | 49 | |||||
DRB | 51 | Side | + | 37 | 50 | 51 | 52 | ||||
DRB | 57 | Top | + | 56 | 57 | 58 | 61 | A76 | P13 | ||
DRB | 58 | Top | + | 54 | 57 | 58 | 59 | 62 | |||
DRB | 59 | Top | ++ | 58 | 59 | 60 | |||||
DRB | 60 | Top | ++ | 59 | 60 | 61 | 63 | ||||
DRB | 67 | Top | + | 66 | 67 | 68 | 71 | ||||
DRB | 70 | Top | + | 67 | 69 | 70 | 71 | 73 | P11 | ||
DRB | 71 | Top | ± | 70 | 71 | 72 | 73 | ||||
DRB | 73 | Top | + | 69 | 72 | 73 | 74 | 76 | 77 | ||
DRB | 74 | Top | + | 70 | 71 | 72 | 73 | 74 | 79 | P8 | P9 |
DRB | 76 | Top | ++ | 73 | 75 | 76 | 77 | ||||
DRB | 77 | Top | ++ | 73 | 76 | 77 | 78 | P6 | |||
DRB | 81 | Top | + | 80 | 81 | 82 | 85 | P4 | |||
DRB | 85 | Top | + | 84 | 85 | 86 | |||||
DRB | 86 | Side | ± | 82 | 85 | 86 | 87 | 90 | |||
DRB | 96 | Side | ++ | 95 | 96 | 97 | 180 | ||||
DRB | 98 | Side | ++ | 97 | 98 | 99 | 120 | ||||
DRB | 104 | Side | + | 103 | 104 | 105 | 107 | 114 | |||
DRB | 105 | Side | ++ | 104 | 105 | 106 | 107 | ||||
DRB | 108 | Side | ++ | 107 | 108 | 109 | |||||
DRB | 112 | Bottom | ++ | 108 | 111 | 112 | 113 | ||||
DRB | 120 | Side | + | 98 | 119 | 120 | 121 | ||||
DRB | 133 | Bottom | ++ | 132 | 133 | 134 | |||||
DRB | 135 | Bottom | ++ | 134 | 135 | 136 | |||||
DRB | 140 | Side | ++ | 139 | 140 | 141 | |||||
DRB | 142 | Side | ++ | 138 | 141 | 142 | 143 | ||||
DRB | 149 | Side | ++ | 148 | 149 | 150 | |||||
DRB | 180 | Side | + | 96 | 177 | 179 | 180 | 181 | |||
DRB | 181 | Side | ++ | 180 | 181 | 182 | |||||
DRB | 183 | Side | + | 182 | 183 | 184 | |||||
DRB | 187 | Side | ++ | 186 | 187 | 188 | |||||
DRB | 189 | Bottom | ++ | 188 | 189 | 190 |
Polymorphic positions are marked in bold, underlined font.