Fig. 3.

Potential molecular arrangements of three apoA-I molecules on the larger HDL spherical particles. The classical 5/5 double belt model proposed for D96 is shown first with two molecules of apoA-I shown in red and green (model A). The small spheres represent the N-terminal 44 aa of each molecule. Model B shows two molecules of apoA-I arranged in a double belt as in the discs with a third molecule arranged as a hairpin on one hemisphere. Model C has all three molecules arranged in an antiparallel fashion at the particle equator, i.e., triple belt. Model D, called the trefoil model, was generated by splitting the right hand half of two molecules of apoA-I in the double belt 60° out of the plane of the disk. Then a third molecule, bent the same way, was inserted.