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. 2008 Aug 21;105(34):12423–12428. doi: 10.1073/pnas.0806372105

Fig. 5.

Fig. 5.

Effects of IL-4/STAT6 deficiency on CD4+GFP+ induction and Th2 effector responses after KLH-induced airway inflammation, anti-IgD injection, or ear model of Th2 induction. (A) Cytometric analysis of mediastinal lymph node CD4+GFP+ cell numbers. (B) FBA of serum IgE levels after KLH challenge. (C) BAL eosinophilia after administration of KLH challenge. (D) Cytometric analysis of mediastinal lymph node CD4+GFP+ cell numbers. (E) FBA of serum IgE levels at day 7 after administration of αIgD. Data points shown indicate mean ± SE from three individual animals. (F) Cytometric analysis of ear-draining lymph node cell numbers after injection of 600 dead L3 Nb. Naive mice (open bars), challenged mice (solid bars). Data were compiled from multiple independent experiments. Statistical analysis was performed by one-way ANOVA with Turkey's post hoc testing, P < 0.001 except where indicated by ns (no significant difference, P > 0.95).