Table 3.
Comparison of seroprevalence of HHV-8, CMV and EBV between HIV-seronegative healthy blood donors and HIV-AIDS patients in Ghana by age and gender
| Patient characteristic | Proportion (%) of HHV-8 seropositives | Proportion (%) of CMV seropositives | Proportion (%) of EBV seropositives | ||||||
| HIV- | HIV+ | *P value | HIV- | HIV+ | *P value | HIV- | HIV+ | *P value | |
| Age group, years | |||||||||
| 16–25 | 169/1016 (16.6) | 24/37 (64.9) | < 0.001 | 790/1016 (77.8) | 22/37 (59.5) | 0.26 | 182/1016 (17.9) | 30/37 (81.1) | < 0.0005 |
| 26–35 | 329/1340 (24.6) | 65/90 (72.2) | < 0.005 | 989/1340 (73.8) | 59/90 (65.6) | 0.45 | 63/1340 (4.7) | 80/90 (88.9) | < 0.0001 |
| 36–45 | 147/552 (26.6) | 45/73 (61.6) | < 0.05 | 480/552 (87.0) | 41/73 (56.2) | 0.10 | 259/552 (46.9) | 65/73 (89.0) | < 0.05 |
| 46–55 | 60/200 (30.0) | 21/36 (58.3) | < 0.05 | 138/200 (69.0) | 18/36 (50.0) | 0.25 | 94/200 (47.0) | 31/36 (86.1) | < 0.05 |
| 56–65 | 72/167 (43.1) | 9/14 (64.3) | < 0.05 | 145/167 (86.8) | 8/14 (57.1) | 0.12 | 58/167 (34.7) | 12/14 (85.7) | < 0.05 |
| Gender | |||||||||
| Male | 567/2573 (22.0) | 88/140 (62.9) | < 0.005 | 2033/2573 (79.0) | 80/140 (57.1) | 0.19 | 482/2573 (18.7) | 122/140 (87.1) | < 0.0005 |
| Female | 210/702 (29.9) | 76/110 (69.1) | < 0.05 | 509/702 (72.5) | 68/110 (61.8) | 0.36 | 174/702 (24.8) | 96/110 (87.3) | < 0.005 |
| Total | 777/3275 (23.7) | 164/250 (65.6) | < 0.005 | 2542/3275 (77.6) | 148/250 (59.2) | 0.24 | 656/3275 (20.0) | 218/250 (87.2) | < 0.001 |
*Comparison between HIV-seronegative blood donors and HIV-AIDS patients using the chi-square test with Yates correction.