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. Author manuscript; available in PMC: 2009 Jan 31.
Published in final edited form as: Nature. 2008 Jul 9;454(7204):642–645. doi: 10.1038/nature07167

Fig. 3.

Fig. 3

D-Sap induced ITC lesions cause an extinction deficit. (a) Percent time freezing (y-axis; mean ± s.e.m.) in ITC-lesioned rats (red; n=8) vs. control rats that received U-Sap infusions at the same site (empty black circles; n=11) or D-Sap infusions in the BLA or CEA (n=15; filled black circles). Data obtained in the D-Sap BLA and CEA animals was pooled because the behavior of these two rat subsets was statistically undistinguishable (ANOVA F(1,108)=0.847, p=0.38). (b) Relationship between number of ITC (bottom) or CEA (top) neurons (y-axis) vs. percent time freezing (x-axis) during extinction testing session (average of first three trials).