. Author manuscript; available in PMC: 2008 Sep 3.

Published in final edited form as: Biochemistry. 2007 Apr 21;46(19):5697–5708. doi: 10.1021/bi602354t

TABLE 2. Comparison of plasma lipids and apoA-I levels and hepatic mRNA levels of apoA-I^-/- mice 4 days post-infection with recombinant adenoviruses expressing the WT apoA-I or apoA-I mutants or the control protein GFP.

	Cholesterol (mg/dl)	Free cholesterol (mg/dl)	Cholesteryl esters (mg/dl)	CE/TC	Phospholipids (mg/dl)	Triglycerides (mg/dl)	ApoA-I (mg/dl)	Relative apoA-I mRNA (%)
WT apoA-I	116±33	36±18	81±18	0.71±0.08	273±52	91±6	216±36	100
apoA-I[Δ(185-243)]	28±3	23±2	5±2	0.17±0.07	69±7	53±13	0.8±0.1	94±17
apoA-I[Δ(220-243)]	43±4	24±1	18±3	0.42±0.03	52±6	51±13	13±3	96±2
apoA-I[Δ(232-243)]	79±17	20±5	59±12	0.75±0.03	142±24	68±8	87±25	100±20
apoA-I[E191A/H193A/K195A]	113±11	30±3	83±9	0.73±0.03	241±35	81±30	183±32	82±13
apoA-I^-/- GFP	27±4	13±3	14±6	0.53±0.09	94±13	37±9	-	-

Values are means ± S.D. (n=4-7).

TABLE 2. Comparison of plasma lipids and apoA-I levels and hepatic mRNA levels of apoA-I-/- mice 4 days post-infection with recombinant adenoviruses expressing the WT apoA-I or apoA-I mutants or the control protein GFP.