Table 2.
Clinical studies of circulating RBP4 levels
Subjects | Major findings | References |
---|---|---|
Obese and T2DM subjects | Elevated in subjects with T2DM | Yang et al., (2005) 66 |
IGT and T2DM subjects | Correlation with the magnitude of IR | Graham et al., (2006) 67 |
IGT and T2DM subjects | Elevated in subjects with IGT or T2DM than normal glucose tolerance | Cho et al., (2006) 68 |
Caucasian menopausal women | No correlation with adiposity | Janke et al., (2006) 72 |
Japanese subjects | No correlation with BMI | Takashima et al., (2006) 168 |
IGT and T2DM subjects | No correlation with IR | Erikstrup et al., (2006) 169 |
Chinese subjects | Correlation with the components of MS | Qi et al., (2007) 69 |
Healthy women | Associated with visceral fat | Lee et al., (2007) 70 |
Chinese subjects | Correlation with visceral adiposity | Jia et al., (2007) 71 |
Non diabetic person | No correlation with IR | Yao-Borengasser et al., (2007) 73 |
Subjects with BMI from 18 to 30 | Negative correlation with insulin sensitivity | Gavi et al., (2007) 74 |
Caucasian without T2DM | Associated with liver fat | Stefan et al., (2007) 76 |
Nondiabetic individuals | Reflected ectopic fat accumulation | Perseghin et al., (2007) 77 |
Obese children | Associated positively with CRP | Balagopal et al., (2007) 170 |
Subjects with morbid obesity | Reduction after weight loss | Haider et al., (2007) 171 |
Obese women | Reduction after weight loss | Vitkova et al., (2007) 172 |
Patients with T2DM | Associated with IR | Takebayashi et al., (2007) 173 |
Women with polycystic ovary syndrome | Elevated than BMI-matched subjects | Tan et al., (2007) 174 |
Nondiabetic men | Negatively associated with insulin secretion | Broch et al., (2007) 175 |
Patients with chronic liver disease | Decreased compared with control subjects | Yagmur et al., (2007) 176 |
Patients with T2DM or CVD | Associated with pro-atherogenic lipoprotein levels | von Eynatten et al., (2007) 177 |