Table I.
Identification of proteins linked to vesicle trafficking
Proteins are listed by canine Ensembl accession numbers with the exception of Naked2 and GFP. SID (sequence ID) represents arbitrary values differentiating indiscernible protein sets; GID (global ID) represents indiscernible protein group identifier; CID (cluster ID) represents protein groups that have common peptides (in the supplemental table, these identifiers are underlined and hyperlinked to their IDPicker Web pages); Unique peptides are the total number of unique peptides that were identified. Spectra list the total number of spectra in the three independent experiments: Exp1/G8 (Experiment 1), Exp2/4t (Experiment 2), and Exp3/G10 (Experiment 3). Acc/ID indicates other accession numbers and IDs. Numbers in the last column are the references reporting a link to basolateral trafficking.
| Protein | SID | GID | CID | Unique peptides | Spectra | Exp1/G8 | Exp2/4t | Exp3/G10 | Description | Acc/ID | Linked to basolateral trafficking |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Q969F2|0969F2_HUMAN | 1 | 794 | 196 | 8 | 18 | 6 | 5 | 7 | Naked cuticle homolog 2 (Naked2) (Homo sapiens) | UniRef100_Q9BSN0 | 1, 2 |
| P42212|GFP_AEQVI | 1 | 793 | 253 | 7 | 9 | 2 | 2 | 5 | GFP (Aequorea victoria) (jellyfish) | ||
| ENSCAFP00000026045 | 1 | 685 | 9 | 51 | 86 | 75 | 5 | 6 | Similar to clathrin heavy chain 1 (CLH-17, splice isoform 2) | ID: LOC480578 (Entrez Gene) | |
| ENSCAFP00000024537 | 1 | 638 | 21 | 36 | 103 | 56 | 18 | 29 | Annexin A2 | Acc: NP_001002961 | 23, 24, 52 |
| ENSCAFP00000002591 | 1 | 91 | 24 | 32 | 123 | 117 | 2 | 4 | Annexin Al (fragment) | Acc:G6JDN3 | 13, 52 |
| ENSCAFP00000018474 | 1 | 468 | 19 | 20 | 30 | 17 | 8 | 5 | Similar to coatomer α subunit (α-coat protein) (α-COP) (HEPCOP) | ID: LOC478973 (Entrez Gene) | |
| ENSCAFP00000015809 | 1 | 406 | 247 | 7 | 10 | 4 | 1 | 5 | Similar to SEC22 vesicle trafficking protein-like 1 (Sec22b) | ID: LOC475816 (Entrez Gene) | |
| ENSCAFP00000025081 | 1 | 653 | 230 | 7 | 13 | 6 | 3 | 4 | Similar to transmembrane trafficking protein 21 (transmembrane emp24-like trafficking protein 10) | ID: LOC610559 (Entrez Gene) | |
| ENSCAFP00000005595 | 1 | 168 | 391 | 5 | 5 | 1 | 3 | 1 | Similar to translocation protein SEC63 homolog | ID: LOC475016 (Entrez Gene) | |
| ENSCAFP00000009784 | 1 | 264 | 343 | 5 | 8 | 5 | 1 | 2 | Similar to ADP-ribosylation factor-like 6-interacting protein 5 | ID: LOC476559 (Entrez Gene) | |
| ENSCAFP00000011273 | 1 | 306 | 365 | 5 | 6 | 3 | 2 | 1 | Similar to coatomer protein complex, subunit β 2 | ID: LOC477088 (Entrez Gene) | |
| ENSCAFP00000027637 | 1 | 718 | 334 | 5 | 14 | 4 | 3 | 7 | Similar to vesicle-associated membrane protein-associated protein A (VAMP-associated protein A) (VAMP-A) (VAP-A) (33-kDa vamp-associated protein) (VAP-33) | ID: LOC480208 (Entrez Gene) | 22 |
| ENSCAFP00000001437 | 1 | 58 | 423 | 4 | 6 | 1 | 2 | 3 | Annexin A13 (annexin XIII) (annexin, intestine-specific) (ISA) | Acc: Q29471 | 25 |
| ENSCAFP00000005060 | 1 | 152 | 396 | 4 | 11 | 5 | 3 | 3 | Caveolin-1 (vesicular integral membrane protein VIP21) | Acc: P33724 | 20 |
| ENSCAFP00000006404 | 1 | 191 | 357 | 4 | 6 | 3 | 2 | 1 | Similar to coatomer protein complex, subunit γ 1 | ID: LOC476517 (Entrez Gene) | |
| ENSCAFP00000012445 | 1 | 330 | 498 | 4 | 4 | 2 | 1 | 1 | Similar to general vesicular transport factor p115 (transcytosis-associated protein) (TAP) (vesicle docking protein) | ID: LOC478430 (Entrez Gene) | |
| ENSCAFP00000024181 | 1 | 629 | 409 | 4 | 7 | 5 | 1 | 1 | Vesicular integral membrane protein VIP36 precursor (lectin, mannose-binding 2) | Acc: P49256 | 21 |
| ENSCAFP00000000331 | 1 | 29 | 521 | 3 | 5 | 2 | 2 | 1 | Transmembrane emp24 domain-containing protein 9 precursor (glycoprotein 25L2) | Acc: Q9BVK6 | |
| ENSCAFP00000002070 | 1 | 80 | 357 | 3 | 4 | 1 | 2 | 1 | Similar to coatomer γ-2 subunit (γ-2 coat protein) (γ-2 COP) | ID: LOC475189 (Entrez Gene) | |
| ENSCAFP00000012933 | 1 | 345 | 547 | 3 | 4 | 1 | 1 | 2 | Similar to transmembrane 9 superfamily protein member 3 precursor | ID: LOC612786 (Entrez Gene) |