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. 2008 Aug 12;99(5):774–780. doi: 10.1038/sj.bjc.6604556

Table 1. List of validated genes found to be differentially regulated in gain 7/8 tumours compared to norm 7/8 tumours.

  Annotation of cDNA Accession no. Locus
Genes upregulated in gain 7/8 tumours
 1 CXCR4: chemokine (C-X-C motif) receptor 4 NM_003467 2q21
 2 EPHA3: EphA3 NM_005233 3p11.2
 3 CTNNB1: catenin (cadherin-associated protein) beta 1, 88 kDa NM_001904 3p21
 4 SLBP: stem-loop (histone)-binding protein NM_006527 4p16.3
 5 BMPR1B: bone morphogenetic protein receptor, type IB NM_001203 4q22–q24
 6 ITGA1: integrin, alpha 1 NM_181501 5p11
 7 CHCHD2; 16.7 kDa protein (LOC51142) NM_016139 7p14.1
 8 BZW1: basic leucine zipper and W2 domains 1 NM_014670 8q22.2–q23/ 2q33
 9 PRKCZ (14-3-3 zeta) NM_145690 8q23.1
 10 SQLE: squalene epoxidase NM_003129 8q24.1
 11 DCD: dermcidin NM_053283 12q13
 12 LIV-1: LIV-1 protein, oestrogen-regulated NM_012319 18q12.1
       
Genes downregulated in gain 7/8 tumours
 13 CALM2: calmodulin 2 (phosphorylase kinase, delta) NM_001743 2p21
 14 GLI3: GLI-Kruppel family member GLI3 NM_000168 7p13
 15 CXCL12/cytokine SDF-1-beta NM_000609 10q11.1
 16 BUB3: budding uninhibited by benzimidazoles 3 homologue NM_004725 10q26