Table 2.
Prevalence of side effects of bupropion SR (range %). Pooled data from trials in Table 1
| Placebo % | Bupropion % | |
|---|---|---|
| Insomniaa | 9–21 | 24–42 |
| Headache | 3–33 | 4–33 |
| Dry mouthb | 4–24 | 6–28 |
| Rash/Pruritus | 7 | 15 |
| Rhinitis | 12–17 | 10–14 |
| Nausea/Vomiting | 5–6 | 9–13 |
| Dizziness | 1–6 | 2–11 |
| Anxiety | 5–11 | 5–9 |
| Flu syndrome | 6–11 | 4–9 |
| Taste perversion | 5 | 6 |
| Constipation | 1 | 5–6 |
| Sweating | 3 | 5 |
| Mood disorder | 4 | 4 |
a
Statistical significance demonstrated in 4 trials (Hurt et al 1997;Jorenby et al 1999; Ahluwalia et al 2002; Dalsgard et al 2004).
b
Statistical significance demonstrated in 2 trials (Hurt et al 1997; Jorenby et al 1999).