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. 2008 Jun;29(4):465–493. doi: 10.1210/er.2007-0041

Figure 2.

Figure 2

Rate and extent of gonadotropin suppression with various hormonal interventions. Normal healthy men ages 18–55 given TE alone (100 mg im every week), TE plus oral levonorgestrel (LNG, 125 mg oral, daily), TE + acyline (300 μg/kg sc on day 0 only), or TE + LNG + acyline (n = 7 per group). Error bars represent ± sem. Rates of suppression were compared using time-to-event analysis with the event defined as suppression of LH or FSH to <1 IU/liter. Suppression of both LH and FSH was accelerated in both groups receiving acyline (P < 0.05) compared with the other two groups. [Data printed with permission of A. D. Coviello and W. J. Bremner.]