Figure 1.

Relationship between percentage of pancreas volume occupied by β-cells and fasting plasma glucose in obese humans without insulin or oral antidiabetic treatment. The solid line is derived from nonlinear regression analysis (monoexponential fit, r = 0.50; P < 0.0001 by ANOVA). The dashed vertical lines indicate the mean β-cell area in obese nondiabetic subjects (OND) (right) and the computed inflection point of the curve (left). IFG, Impaired fasting glucose; OD, obese diabetic. Adapted from Ref. 11. [Copyright 2006 American Diabetes Association. From Diabetes Care 29:717–718. Reprinted with permission from The American Diabetes Association.]