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Human islets from T2DM subjects (right) have less β-cells than those from nondiabetic subjects (left) and contain deposits of amyloid (arrow) derived from IAPP. Human islets were stained for insulin. This figure originally appeared in an article by Matveyenko and Butler (39). It is reprinted with permission from the ILAR Journal, Institute for Laboratory Animal Research, The National Academies (www.nationalacademies.org/ilar).
