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. Author manuscript; available in PMC: 2008 Sep 3.
Published in final edited form as: J Med Chem. 2007 May 10;50(11):2622–2639. doi: 10.1021/jm0613323

Figure 7.

Figure 7

3-Cl-AHPC (5) induces apoptosis of HMVE cells. Cells were incubated for 20 h in the presence of Me2SO (negative control), positive control doxorubicin (1.0 µM), or 5 (10 nM to 500 nM) and assayed for apoptosis using a cell death detection ELISA as described in the the Experimental Section. Values represent the enrichment of mono- and oligonucleosome levels in treated sample relative to Me2SO control, and each bar represents the mean ± SD. Statistically significant differences (Student’s t-test) compared with Me2SO control are indicated (*, p < 0.05; **, p < 0.001).