TABLE 1.
Clinical findings and risk of sudden unexpected cardiac death (SUCD): Manitoba Follow-up Study, 1948–2004
Time since detection of finding (RR [95% CI])
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Clinical finding | Number (% of cohort) | Age (years), mean ± SD | Number with SUCD | Age-adjusted RR (95% CI) | Attributable risk | 1 day to 5 years | Five to 10 years | Over 10 years |
High heart rate | 755 (19.0) | 53.8±19.1 | 33 | 1.92 (1.31–2.82) | 0.15 | 2.53 (1.24–5.19) | 2.13 (0.87–5.22) | 1.71 (1.07–2.75) |
Overweight | 1949 (48.9) | 41.4±12.0 | 100 | 1.75 (1.29–2.38) | 0.27 | 0.51 (0.12–2.08) | 1.39 (0.64–3.04) | 1.91 (1.39–2.62) |
Obesity | 635 (15.9) | 48.7±13.1 | 34 | 1.61 (1.10–2.36) | 0.09 | 0.79 (0.20–3.20) | 2.80 (1.36–5.72) | 1.52 (0.97–2.37) |
Diabetes | 395 (9.9) | 63.2±11.0 | 19 | 2.14 (1.31–3.48) | 0.10 | 2.43 (1.14–5.20) | 0.86 (0.21–3.46) | 2.74 (1.42–5.28) |
Hypertension | 1529 (38.4) | 58.0±11.8 | 77 | 2.29 (1.66–3.16) | 0.33 | 1.79 (1.02–3.16) | 1.82 (1.01–3.28) | 2.77 (1.90–4.04) |
Isolated systolic hypertension | 373 (9.4) | 69.3±9.40 | 14 | 1.54 (0.87–2.72) | 0.05 | 1.19 (0.44–3.23) | 1.51 (0.55–4.12) | 2.00 (0.86–4.64) |
Pulse pressure | 1824 (45.8) | 60.8±12.9 | 80 | 2.07 (1.48–2.90) | 0.29 | 1.55 (0.90–2.68) | 2.14 (1.28–3.59) | 2.40 (1.60–3.60) |
Alcohol abuse | 346 (8.7) | 59.6±11.4 | 18 | 2.85 (1.74–4.66) | 0.10 | 5.92 (3.19–10.96) | 1.34 (0.33–5.42) | 1.67 (0.68–4.09) |
Stroke | 431 (10.8) | 70.2±10.5 | 14 | 1.99 (1.13–3.50) | 0.10 | 2.85 (1.44–5.64) | 1.68 (0.53–5.32) | 0.95 (0.23–3.87) |
Peripheral vascular disease | 291 (7.3) | 67.6±10.5 | 11 | 1.90 (1.02–3.54) | 0.06 | 2.47 (1.08–5.62) | 1.99 (0.63–6.30) | 1.07 (0.26–4.35) |