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. 2008 Aug 28;105(35):13021–13026. doi: 10.1073/pnas.0803304105

Fig. 2.

Fig. 2.

Kaplan–Meier TDM curves of primary breast cancer patients based on miRNA expression levels. Kaplan–Meier TDM curves for 147 ER+/LNN cases as a function of four subgroups (clusters 1–4) revealed by hierarchical clustering of the samples based on the levels of miR-7, miR-128a, miR-210, and miR-516-3p (clustering plot is shown above the Kaplan–Meier curve) (A) and as a function of three equally sized subgroups (quantiles 1–3) based on a score of the coefficients of the multivariable Cox regression model of miR-7, miR-128a, miR-210, and miR-516-3p as continuous variables (B). (C) Kaplan–Meier TDM curves for 69 triple-negative (ER−/PgR−/Her-2−) breast cancer cases as a function of subgroups dichotomized at the median miR-210 expression level. Patients at risk at the indicated time intervals are shown at the bottom of each graph.