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. 2008 Aug 26;105(35):12961–12966. doi: 10.1073/pnas.0806180105

Fig. 2.

Fig. 2.

Retarded growth and postnatal lethality of striatum-specific NR1-deficient mice. (A) Smaller body size of the P16 knockout mice (fNR1/fNR1, Cre/+) placed above a P16 control animal. (Scale bar, 10 mm.) (B) Postnatal developmental growth curve of each genotype. Data are expressed as mean +/− SD. Reduced body weight of mutant pups (fNR1/fNR1, Cre/+) became significant from P13 against all other genotypes (*, P < 0.05 and **, P < 0.01 after P14, post hoc analyses). (C) Reduced food intake by the mutant mice (P16) compared with their control littermates (n = 6). (D) Percentage distribution of mortality in the conditional knockout mice (n = 21). Average lifespan = 19.97 (days) +/− 2.87 (SD). The distribution was leptokurtic (Kurtosis = 4.37).