Table 3.
Assessing risk factors in disease severity.
| Risk factor | Frequency | Mean severity score in presence of factor | Mean severity score in absence of factor | Significance of risk factor on severity (p value) |
|---|---|---|---|---|
| Positive family history | 35/92 (38%) | 23.1 | 15.9 | 0.006 |
| Substantial alcohol history | 20/92 (22%) | 24.6 | 17.0 | 0.04 |
| Manual labor | 58/92 (63%) | 19.8 | 16.7 | 0.20 |
| Diabetes mellitus | 13/92 (14%) | 22.1 | 18.1 | 0.31 |
| Smoker | 45/92 (49%) | 19.8 | 17.6 | 0.34 |
| Carpal tunnel syndrome | 4/92 (4%) | 23.5 | 18.5 | 0.39 |
| Age at onset <55 years | 34/92 (37%) | 19.4 | 18.2 | 0.62 |
| Male gender | 80/92 (87%) | 18.5 | 19.3 | 0.71 |
| Frozen shoulder | 18/92 (20%) | 19.3 | 18.5 | 0.80 |
| Rheumatoid arthritis | 3/92 (3%) | 19.3 | 18.6 | 0.95 |
| Hand injury | 9/92 (9%) | 18.6 | 18.6 | 0.99 |
List of known associated risk factors and their significance in Dupuytren’s disease severity